Author Archives: Medicine is life

Pharmacist

Nimesulide

Nimesulide is a nonsteroidal anti-inflammatory drug with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems.

Boiling point: 442 °C

Metabolism: Hepatic

Excretion: Renal (50%), fecal (29%)

ATC code: M01AX17 (WHO) M02AA26 (WHO)

AHFS/Drugs.com: International Drug Names

Elimination half-life: 1.8–4.7h

PubChem CID: 4495

Paracetamol

Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior to ibuprofen in that respect, and the benefits of its use for fever are unclear.

Formula: C8H9NO2

Molar mass: 151.163 g/mol

Melting point: 169 °C

Metabolism: Predominantly in the liver

Other names: N-acetyl-para-aminophenol (APAP), acetaminophen (USAN US)

Onset of action: Pain relief onset by route: By mouth – 37 minutes; Intravenous

– 8 minutes

IUPAC ID: N-(4-hydroxyphenyl)acetamide, N-(4-hydroxyphenyl)ethanamide